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Target
Platelet-activating factor acetylhydrolase [136-227]
Ligand
BDBM50040461
Substrate
n/a
Meas. Tech.
ChEMBL_156342 (CHEMBL759985)
IC50
15±n/a nM
Citation
 Beaton, HG; Bennion, C; Connolly, S; Cook, AR; Gensmantel, NP; Hallam, C; Hardy, K; Hitchin, B; Jackson, CG; Robinson, DH Discovery of new non-phospholipid inhibitors of the secretory phospholipases A2. J Med Chem 37:557-9 (1994) [PubMed]  Article 
Target
Name:
Platelet-activating factor acetylhydrolase [136-227]
Synonyms:
A0A5G2RFL7_PIG | Group VII phospholipase A2 | PLA2G7
Type:
PROTEIN
Mol. Mass.:
10360.56
Organism:
Sus scrofa
Description:
ChEMBL_156342
Residue:
92
Sequence:
SPLRTGEKYPLIIFSHGLGAFRTIYSAIGTDLASYGFIVAAVEHRDGSASATYFFKDQSAAEIRNKTWLYLRTLGKGEEEFPLRNEQVRQRA
  
Inhibitor
Name:
BDBM50040461
Synonyms:
(S)-5-(4-Benzyl-phenylsulfanyl)-4-((S)-7-phenyl-heptanoylamino)-pentanoic acid | (S)-5-(4-Benzyl-phenylsulfanyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid | CHEMBL434630
Type:
Small organic molecule
Emp. Form.:
C31H37NO3S
Mol. Mass.:
503.695
SMILES:
OC(=O)CC[C@@H](CSc1ccc(Cc2ccccc2)cc1)NC(=O)CCCCCCc1ccccc1
Structure:
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