Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50494106
Substrate
n/a
Meas. Tech.
ChEMBL_990337 (CHEMBL2445750)
Ki
136±n/a nM
Citation
 Petrov, RR; Knight, L; Chen, SR; Wager-Miller, J; McDaniel, SW; Diaz, F; Barth, F; Pan, HL; Mackie, K; Cavasotto, CN; Diaz, P Mastering tricyclic ring systems for desirable functional cannabinoid activity. Eur J Med Chem 69:881-907 (2013) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50494106
Synonyms:
CHEMBL2441450
Type:
Small organic molecule
Emp. Form.:
C22H27N3O
Mol. Mass.:
349.4693
SMILES:
CCCCCn1c2ccccc2c2cc(ncc12)C(=O)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: