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Target
Cannabinoid receptor 1
Ligand
BDBM50312839
Substrate
n/a
Meas. Tech.
ChEMBL_1278954 (CHEMBL3097437)
Ki
>1000±n/a nM
Citation
 Lueg, C; Schepmann, D; Günther, R; Brust, P; Wünsch, B Development of fluorinated CB(2) receptor agonists for PET studies. Bioorg Med Chem 21:7481-98 (2013) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50312839
Synonyms:
CHEMBL1081622 | [18F]8-butoxy-N-cyclohexyl-7-(2-fluoroethoxy)-2-oxo-1,2-dihydroquinoline-3-carboxamide
Type:
Small organic molecule
Emp. Form.:
C22H29FN2O4
Mol. Mass.:
404.4751
SMILES:
CCCCOc1c(OCCF)ccc2cc(C(=O)NC3CCCCC3)c(=O)[nH]c12
Structure:
Search PDB for entries with ligand similarity: