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Target
D(2) dopamine receptor
Ligand
BDBM50041960
Substrate
n/a
Meas. Tech.
ChEMBL_59484 (CHEMBL879870)
Ki
1720±n/a nM
Citation
 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikström, H Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. J Med Chem 36:3188-96 (1993) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50041960
Synonyms:
(+)-3-(1-Propyl-piperidin-3-yl)-benzonitrile | (-)-3-(1-Propyl-piperidin-3-yl)-benzonitrile | 3-(1-Propyl-piperidin-3-yl)-benzonitrile | CHEMBL107492
Type:
Small organic molecule
Emp. Form.:
C15H20N2
Mol. Mass.:
228.3327
SMILES:
CCCN1CCCC(C1)c1cccc(c1)C#N
Structure:
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