Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM50022721
Substrate
n/a
Meas. Tech.
ChEMBL_1287607 (CHEMBL3110489)
EC50
105±n/a nM
Citation
 Reese, EA; Norimatsu, Y; Grandy, MS; Suchland, KL; Bunzow, JR; Grandy, DK Exploring the determinants of trace amine-associated receptor 1's functional selectivity for the stereoisomers of amphetamine and methamphetamine. J Med Chem 57:378-90 (2014) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
Trace amine receptor 1 (TARR1) | Trace amine-associated receptor1 | TAAR1_MOUSE | Taar1 | Ta1 | Tar1 | Trar1 | Trace amine-associated receptor 1 (TAAR1)
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mouse
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM50022721
Synonyms:
(R)-amphetamine | CHEMBL19393 | AMPHETAMINE
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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