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Target
D(2) dopamine receptor
Ligand
BDBM50046488
Substrate
n/a
Meas. Tech.
ChEMBL_62563 (CHEMBL671494)
Ki
6±n/a nM
Citation
 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Synthesis and in vitro evaluation of 5,6,7,8,9,10-hexahydro-7,10-iminocyclohept[b]indoles: high-affinity ligands for the N,N'-di-o-tolylguanidine-labeled sigma binding site. J Med Chem 36:343-52 (1993) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50046488
Synonyms:
8-Fluoro-2-(3-pyridin-4-yl-propyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | CHEMBL442395
Type:
Small organic molecule
Emp. Form.:
C19H20FN3
Mol. Mass.:
309.3806
SMILES:
Fc1ccc2[nH]c3CCN(CCCc4ccncc4)Cc3c2c1
Structure:
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