Reaction Details Report a problem with these data
Target
Carbonic anhydrase 14
Ligand
BDBM50500675
Substrate
n/a
Meas. Tech.
ChEMBL_1549340 (CHEMBL3755046)
Ki
7.7±n/a nM
Citation
 Villalba, ML; Palestro, P; Ceruso, M; Gonzalez Funes, JL; Talevi, A; Bruno Blanch, L; Supuran, CT; Gavernet, L Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action. Bioorg Med Chem 24:894-901 (2016) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 14
Synonyms:
CA-XIV | CA14 | CAH14_HUMAN | Carbonate dehydratase XIV | Carbonic Anhydrase XIV | Carbonic anhydrase | Carbonic anhydrase 14 | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV)
Type:
Enzyme
Mol. Mass.:
37665.67
Organism:
Homo sapiens (Human)
Description:
Human (cloned) isozyme.
Residue:
337
Sequence:
MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
  
Inhibitor
Name:
BDBM50500675
Synonyms:
CHEMBL3752037
Type:
Small organic molecule
Emp. Form.:
C14H22N2O4S
Mol. Mass.:
314.4
SMILES:
COC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)NCC(C)C |r|
Structure:
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