Affinity DataKi: 0.0700nMAssay Description:Inhibition of human carbonic anhydrase-2More data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Inhibition of human carbonic anhydrase-2 incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2 [A65S,N67Q,E69T,I91L,F131V,K170E,L204A](Homo sapiens (Human))
University of Florida
University of Florida
Affinity DataKi: 0.200nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2 [A65S,N67Q,E69T,I91L,F131V,K170E,L204A](Homo sapiens (Human))
University of Florida
University of Florida
Affinity DataKi: 0.200nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 ADR expressed in HEK293T cell membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Inhibition of human carbonic anhydrase-2 incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of human carbonic anhydrase-2 incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of carbonic anhydrase-2 (unknown origin) incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of human carbonic anhydrase-7 preincubated for 15 mins by stopped flow CO2 dehydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibition of human carbonic anhydrase-7 preincubated for 15 mins by stopped flow CO2 dehydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Inhibition of human carbonic anhydrase-12More data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Inhibition of human carbonic anhydrase-7 preincubated for 15 mins by stopped flow CO2 dehydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow carbon dioxide hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Inhibition of human carbonic anhydrase-12 incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow carbon dioxide hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Inhibition of human carbonic anhydrase 12 using saturated CO2 as substrate incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Inhibition of human carbonic anhydrase-12 incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Inhibition of human carbonic anhydrase-2 incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Inhibition of human carbonic anhydrase-12 incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Inhibition of human carbonic anhydrase-12 incubated for 10 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow carbon dioxide hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins prior to testing by CO2 hydration-based stopped flow assayMore data for this Ligand-Target Pair