Reaction Details Report a problem with these data
Target
Quinone oxidoreductase
Ligand
BDBM50505034
Substrate
n/a
Meas. Tech.
ChEMBL_1817032 (CHEMBL4316692)
IC50
48000±n/a nM
Citation
 Nepali, K; Lee, HY; Liou, JP Nitro-Group-Containing Drugs. J Med Chem 62:2851-2893 (2019) [PubMed]  Article 
Target
Name:
Quinone oxidoreductase
Synonyms:
1.6.5.5 | CRYZ | NADPH:quinone reductase | QOR_HUMAN | Quinone oxidoreductase | Zeta-crystallin
Type:
PROTEIN
Mol. Mass.:
35214.26
Organism:
Homo sapiens
Description:
ChEMBL_102762
Residue:
329
Sequence:
MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL
  
Inhibitor
Name:
BDBM50505034
Synonyms:
CHEMBL213994
Type:
Small organic molecule
Emp. Form.:
C13H18Cl2N3O4P
Mol. Mass.:
382.179
SMILES:
[O-][N+](=O)c1ccc(cc1)C1CCOP(=O)(N1)N(CCCl)CCCl
Structure:
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