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Found 971 with Last Name = 'liou' and Initial = 'jp'
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50546246(CHEMBL4753043 | US11608319, Compound AR-13503)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human ROCK1 expressed in baculovirus expression system by Kinase-Glo luminescent AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50546246(CHEMBL4753043 | US11608319, Compound AR-13503)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human ROCK2 expressed in baculovirus expression system by Kinase-Glo luminescent AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM108255(US8609833, 86)
Affinity DataKi:  0.970nMAssay Description:Binding affinity to A1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50118812((2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylami...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to A3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50598611(CHEMBL5187502)
Affinity DataKi:  4nMAssay Description:Binding affinity to TSPO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50546247(AR-11324 FREE BASE | AR-13324 | Netarsudil | US114...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of human ROCK2 by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  38nMAssay Description:Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070947(2-ethyl-1'-methylspiro[2,3-dihydrobenzo[b]furan-3,...)
Affinity DataKi:  102nMAssay Description:Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070948(1',2-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-(...)
Affinity DataKi:  124nMAssay Description:Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50026752(1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...)
Affinity DataKi:  451nMAssay Description:Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070946(1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-...)
Affinity DataKi:  505nMAssay Description:Binding affinity of the compound against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070946(1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-...)
Affinity DataKi:  505nMAssay Description:Binding affinity against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  510nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070947(2-ethyl-1'-methylspiro[2,3-dihydrobenzo[b]furan-3,...)
Affinity DataKi:  853nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070946(1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-...)
Affinity DataKi:  1.01E+3nMAssay Description:Binding affinity against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070946(1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-...)
Affinity DataKi:  1.02E+3nMAssay Description:Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070949(1'-methylspiro[2,3-dihydrobenzo[b]furan-3,4'-(hexa...)
Affinity DataKi:  1.65E+3nMAssay Description:Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  1.87E+3nMAssay Description:Binding affinity of the compound against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50548039(CHEMBL4798513)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of human LSD1 preincubated for 10 mins followed by H3(1-20)K4-dimethylated (K4me2) peptide substrate addition and measured after 30 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070948(1',2-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-(...)
Affinity DataKi:  2.41E+3nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50026752(1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity of the compound against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070948(1',2-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-(...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity of the compound against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070949(1'-methylspiro[2,3-dihydrobenzo[b]furan-3,4'-(hexa...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070949(1'-methylspiro[2,3-dihydrobenzo[b]furan-3,4'-(hexa...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity of the compound against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070947(2-ethyl-1'-methylspiro[2,3-dihydrobenzo[b]furan-3,...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity of the compound against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50603177(CHEMBL5200566)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of MAO-A (unknown origin) expressed in mouse GL26 cells using 14C 5-hydroxytryptamine as substrate pre-incubated for 20 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50245492(CHEMBL4082554)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using pro-TNFalpha peptide Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241905(CHEMBL4080164)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of recombinant human full length HDAC2 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505038(CHEMBL4516232)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505039(CHEMBL4439982)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505037(CHEMBL4473277)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505036(CHEMBL4540138)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505035(CHEMBL4527121)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50505040(CHEMBL4560430)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of erbB1 (unknown origin) using FRET-capable peptide substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247556(CHEMBL4104117)
Affinity DataIC50:  0.291nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50603180(CHEMBL5178014)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of MAO-A (unknown origin) expressed in mouse GL26 cells using 14C 5-hydroxytryptamine as substrate pre-incubated for 20 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of recombinant human full length HDAC2 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50236621(CHEMBL4078142)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using pro-TNFalpha peptide Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataIC50:  0.610nMAssay Description:Inhibition of human full length recombinant MAO-A expressed in insect cells using kynuramine as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50245498(CHEMBL4083562)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of recombinant human ASK1 using STK3 peptide as substrate incubated for 30 mins followed by ATP addition measured for 3 hrs by TR-FRET ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50247553(CHEMBL4095667)
Affinity DataIC50:  0.795nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241906(CHEMBL4069853)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of recombinant human full length HDAC2 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50386657(CHEMBL2048746)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MAO-A (unknown origin) expressed in mouse GL26 cells using 14C 5-hydroxytryptamine as substrate pre-incubated for 20 mins followed by s...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241905(CHEMBL4080164)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of HDAC6 (unknown origin) by colorimetric methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241906(CHEMBL4069853)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human recombinant HDAC2 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM24346(N-(4-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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