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Target
Integrase
Ligand
BDBM50056899
Substrate
n/a
Meas. Tech.
ChEMBL_90707 (CHEMBL702106)
IC50
>100000±n/a nM
Citation
 Zhao, H; Neamati, N; Sunder, S; Hong, H; Wang, S; Milne, GW; Pommier, Y; Burke, TR Hydrazide-containing inhibitors of HIV-1 integrase. J Med Chem 40:937-41 (1997) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50056899
Synonyms:
2-Hydroxy-benzoic acid N'-(2-amino-benzoyl)-hydrazide | CHEMBL173334
Type:
Small organic molecule
Emp. Form.:
C14H13N3O3
Mol. Mass.:
271.2713
SMILES:
Nc1ccccc1C(=O)NNC(=O)c1ccccc1O
Structure:
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