Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM85776
Substrate
n/a
Meas. Tech.
ChEMBL_30484 (CHEMBL641436)
Ki
1420±n/a nM
Citation
 Jiang, J; van Rhee, AM; Chang, L; Patchornik, A; Ji, XD; Evans, P; Melman, N; Jacobson, KA Structure-activity relationships of 4-(phenylethynyl)-6-phenyl-1,4-dihydropyridines as highly selective A3 adenosine receptor antagonists. J Med Chem 40:2596-608 (1997) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3
Type:
PROTEIN
Mol. Mass.:
36643.73
Organism:
Rattus norvegicus
Description:
ChEMBL_479910
Residue:
320
Sequence:
MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE
  
Inhibitor
Name:
BDBM85776
Synonyms:
CAS_393594 | CHEMBL89852 | MRS1191 | NSC_393594
Type:
Small organic molecule
Emp. Form.:
C31H27NO4
Mol. Mass.:
477.5504
SMILES:
CCOC(=O)C1C(C#Cc2ccccc2)C(C(=O)OCc2ccccc2)=C(N=C1C)c1ccccc1 |c:27,29|
Structure:
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