Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50508916
Substrate
n/a
Meas. Tech.
ChEMBL_1835584 (CHEMBL4335717)
IC50
780±n/a nM
Citation
 Bortolozzi, R; Carta, D; Prà, MD; Antoniazzi, G; Mattiuzzo, E; Sturlese, M; Di Paolo, V; Calderan, L; Moro, S; Hamel, E; Quintieri, L; Ronca, R; Viola, G; Ferlin, MG Evaluating the effects of fluorine on biological properties and metabolic stability of some antitubulin 3-substituted 7-phenyl-pyrroloquinolinones. Eur J Med Chem 178:297-314 (2019) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50508916
Synonyms:
CHEMBL4441475
Type:
Small organic molecule
Emp. Form.:
C19H15FN2O
Mol. Mass.:
306.3336
SMILES:
CCn1ccc2c1ccc1[nH]c(cc(=O)c21)-c1cccc(F)c1
Structure:
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