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Found 140 with Last Name = 'ronca' and Initial = 'r'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50300802(5-Morpholin-4-ylpentanoic acid(4-pyridin-3-ylpheny...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]epibatidine from rat rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity to 5HT4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of FLT3 ITD mutant (unknown orgin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50604641(CHEMBL5183674)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of FLT3 ITD mutant (unknown orgin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517548(CHEMBL4460381)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50:  3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of wild type FLT3 (unknown origin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50604641(CHEMBL5183674)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of wild type FLT3 (unknown origin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50604642(CHEMBL5206333)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of FLT3 ITD mutant (unknown orgin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517546(CHEMBL4473768)
Affinity DataIC50:  10nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Palermo

Curated by ChEMBL
LigandPNGBDBM50604642(CHEMBL5206333)
Affinity DataIC50:  14nMAssay Description:Inhibition of wild type FLT3 (unknown origin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517547(CHEMBL4541014)
Affinity DataIC50:  23nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517542(CHEMBL4569885)
Affinity DataIC50:  30nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517545(CHEMBL4546122)
Affinity DataIC50:  52nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50:  80nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50137204((2-Methyl-1H-indol-5-yl)-(6-phenyl-thieno[3,2-d]py...)
Affinity DataIC50:  100nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  140nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50137204((2-Methyl-1H-indol-5-yl)-(6-phenyl-thieno[3,2-d]py...)
Affinity DataIC50:  140nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517544(CHEMBL4552482)
Affinity DataIC50:  273nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528631(CHEMBL4526719)
Affinity DataIC50:  300nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517543(CHEMBL4572443)
Affinity DataIC50:  326nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528630(CHEMBL4440494)
Affinity DataIC50:  340nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528642(CHEMBL4447541)
Affinity DataIC50:  350nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528635(CHEMBL4473254)
Affinity DataIC50:  360nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528638(CHEMBL4442113)
Affinity DataIC50:  370nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528629(CHEMBL4524533)
Affinity DataIC50:  370nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50508919(CHEMBL4459174)
Affinity DataIC50:  380nMAssay Description:Inhibition of bovine brain tubulin polymerization preincubated for 15 mins followed by GTP addition and measured for 20 mins by turbidimetry-based sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528636(CHEMBL4464909)
Affinity DataIC50:  390nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528641(CHEMBL4436465)
Affinity DataIC50:  410nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528633(CHEMBL4522990)
Affinity DataIC50:  420nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528634(CHEMBL4554434)
Affinity DataIC50:  440nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528640(CHEMBL4551856)
Affinity DataIC50:  480nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528644(CHEMBL4449830)
Affinity DataIC50:  480nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528645(CHEMBL4451991)
Affinity DataIC50:  520nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528639(CHEMBL4525021)
Affinity DataIC50:  520nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  540nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528637(CHEMBL4541938)
Affinity DataIC50:  570nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528643(CHEMBL4533893)
Affinity DataIC50:  570nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50508917(CHEMBL236350)
Affinity DataIC50:  570nMAssay Description:Inhibition of bovine brain tubulin polymerization preincubated for 15 mins followed by GTP addition and measured for 20 mins by turbidimetry-based sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50528632(CHEMBL4459196)
Affinity DataIC50:  610nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  640nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  640nMAssay Description:Inhibition of bovine brain tubulin polymerization preincubated for 15 mins followed by GTP addition and measured for 20 mins by turbidimetry-based sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50517542(CHEMBL4569885)
Affinity DataIC50:  710nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50508916(CHEMBL4441475)
Affinity DataIC50:  780nMAssay Description:Inhibition of bovine brain tubulin polymerization preincubated for 15 mins followed by GTP addition and measured for 20 mins by turbidimetry-based sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50508915(CHEMBL4440522)
Affinity DataIC50:  960nMAssay Description:Inhibition of bovine brain tubulin polymerization preincubated for 15 mins followed by GTP addition and measured for 20 mins by turbidimetry-based sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517548(CHEMBL4460381)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of wild type VEGFR2 (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517547(CHEMBL4541014)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of wild type VEGFR2 (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50517546(CHEMBL4473768)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of wild type VEGFR2 (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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