Reaction Details Report a problem with these data
Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50510090
Substrate
n/a
Meas. Tech.
ChEMBL_1840162 (CHEMBL4340377)
EC50
1000±n/a nM
Citation
 Bermejo, A; Collado, A; Barrachina, I; Marqués, P; El Aouad, N; Franck, X; Garibotto, F; Dacquet, C; Caignard, DH; Suvire, FD; Enriz, RD; Piqueras, L; Figadère, B; Sanz, MJ; Cabedo, N; Cortes, D Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPAR?/PPAR? Agonist Activity and Anti-inflammatory Effect. J Nat Prod 82:1802-1812 (2019) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARγ) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50510090
Synonyms:
CHEMBL4535730
Type:
Small organic molecule
Emp. Form.:
C23H32O4
Mol. Mass.:
372.4978
SMILES:
COc1cc(C)c2O[C@](C)(CC\C=C(/C)CC\C=C(/C)C(O)=O)CCc2c1 |r|
Structure:
Search PDB for entries with ligand similarity: