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Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50513140
Substrate
n/a
Meas. Tech.
ChEMBL_1852096 (CHEMBL4352720)
IC50
500±n/a nM
Citation
 Niu, H; Strecker, TE; Gerberich, JL; Campbell, JW; Saha, D; Mondal, D; Hamel, E; Chaplin, DJ; Mason, RP; Trawick, ML; Pinney, KG Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization. J Med Chem 62:5594-5615 (2019) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50513140
Synonyms:
CHEMBL2022435
Type:
Small organic molecule
Emp. Form.:
C20H22O5
Mol. Mass.:
342.3857
SMILES:
COc1ccc2C(=CCCc2c1O)c1cc(OC)c(OC)c(OC)c1 |c:6|
Structure:
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