Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50513686
Substrate
n/a
Meas. Tech.
ChEMBL_1853918 (CHEMBL4354542)
EC50
12±n/a nM
Citation
 Li, Z; Liu, C; Yang, J; Zhou, J; Ye, Z; Feng, D; Yue, N; Tong, J; Huang, W; Qian, H Design, synthesis and biological evaluation of novel FFA1/GPR40 agonists: New breakthrough in an old scaffold. Eur J Med Chem 179:608-622 (2019) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50513686
Synonyms:
CHEMBL4575598
Type:
Small organic molecule
Emp. Form.:
C24H24FNO4
Mol. Mass.:
409.4501
SMILES:
CCOc1ccc(c(C)c1)-c1cccc(CNc2ccc(OCC(O)=O)c(F)c2)c1
Structure:
Search PDB for entries with ligand similarity: