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Target
Mu-type opioid receptor
Ligand
BDBM50370595
Substrate
n/a
Meas. Tech.
ChEMBL_1859900 (CHEMBL4360756)
EC50
25±n/a nM
Citation
 Dvorácskó, S; Keresztes, A; Mollica, A; Stefanucci, A; Macedonio, G; Pieretti, S; Zádor, F; Walter, FR; Deli, MA; Kékesi, G; Bánki, L; Tuboly, G; Horváth, G; Tömböly, C Preparation of bivalent agonists for targeting the mu opioid and cannabinoid receptors. Eur J Med Chem 178:571-588 (2019) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | Opiate non-selective | Opioid receptor B | OPRM_RAT | Oprm1 | Ror-b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44503.11
Organism:
Rat
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:
398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50370595
Synonyms:
US9233167, Oxycodone | Oxycontin | OXYCODONE | US1184575, oxycodone
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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