Reaction Details Report a problem with these data
Target
Gamma-glutamyl hydrolase
Ligand
BDBM50070540
Substrate
n/a
Meas. Tech.
ChEBML_68750
Ki
950000±n/a nM
Citation
 Rodriguez, CE; Holmes, HM; Mlodnosky, KL; Lam, VQ; Berkman, CE Evaluation of phosphorus-containing inhibitors of gamma-glutamyl hydrolase. Bioorg Med Chem Lett 8:1521-4 (1999) [PubMed]  Article 
Target
Name:
Gamma-glutamyl hydrolase
Synonyms:
GGH | GGH_HUMAN
Type:
PROTEIN
Mol. Mass.:
35966.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_68750
Residue:
318
Sequence:
MASPGCLLCVLGLLLCGAASLELSRPHGDTAKKPIIGILMQKCRNKVMKNYGRYYIAASYVKYLESAGARVVPVRLDLTEKDYEILFKSINGILFPGGSVDLRRSDYAKVAKIFYNLSIQSFDDGDYFPVWGTCLGFEELSLLISGECLLTATDTVDVAMPLNFTGGQLHSRMFQNFPTELLLSLAVEPLTANFHKWSLSVKNFTMNEKLKKFFNVLTTNTDGKIEFISTMEGYKYPVYGVQWHPEKAPYEWKNLDGISHAPNAVKTAFYLAEFFVNEARKNNHHFKSESEEEKALIYQFSPIYTGNISSFQQCYIFD
  
Inhibitor
Name:
BDBM50070540
Synonyms:
(2S)-2-{[hydroxy(phenyl)phosphoryl]amino}pentanedioic acid | CHEMBL291301
Type:
Small organic molecule
Emp. Form.:
C11H14NO6P
Mol. Mass.:
287.2057
SMILES:
OC(=O)CC[C@H](NP(O)(=O)c1ccccc1)C(O)=O
Structure:
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