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Target
Histamine H3 receptor
Ligand
BDBM50071196
Substrate
n/a
Meas. Tech.
ChEBML_86899
Ki
42±n/a nM
Citation
 Stark, H; Ligneau, X; Arrang, JM; Schwartz, JC; Schunack, W General construction pattern of histamine H3-receptor antagonists: change of a paradigm. Bioorg Med Chem Lett 8:2011-6 (1999) [PubMed]  Article 
Target
Name:
Histamine H3 receptor
Synonyms:
HH3R | HRH3_RAT | Hrh3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
48607.98
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
  
Inhibitor
Name:
BDBM50071196
Synonyms:
4-((E)-6-Phenyl-hex-3-enyl)-1H-imidazole | CHEMBL292250
Type:
Small organic molecule
Emp. Form.:
C15H18N2
Mol. Mass.:
226.3168
SMILES:
C(Cc1cnc[nH]1)C=CCCc1ccccc1 |w:8.9|
Structure:
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