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Target
Histamine H3 receptor
Ligand
BDBM50071197
Substrate
n/a
Meas. Tech.
ChEBML_86899
Ki
56±n/a nM
Citation
 Stark, H; Ligneau, X; Arrang, JM; Schwartz, JC; Schunack, W General construction pattern of histamine H3-receptor antagonists: change of a paradigm. Bioorg Med Chem Lett 8:2011-6 (1999) [PubMed]  Article 
Target
Name:
Histamine H3 receptor
Synonyms:
HH3R | HRH3_RAT | Hrh3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
48607.98
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
  
Inhibitor
Name:
BDBM50071197
Synonyms:
4-(4-Phenyl-butyl)-1H-imidazole | CHEMBL296450
Type:
Small organic molecule
Emp. Form.:
C13H16N2
Mol. Mass.:
200.2795
SMILES:
C(CCc1ccccc1)Cc1cnc[nH]1
Structure:
Search PDB for entries with ligand similarity: