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Target
D(2) dopamine receptor
Ligand
BDBM50516521
Substrate
n/a
Meas. Tech.
ChEMBL_1865788 (CHEMBL4366763)
Ki
734±n/a nM
Citation
 Ali, W; Wi?cek, M; ?a?ewska, D; Kurczab, R; Jastrz?bska-Wi?sek, M; Sata?a, G; Kucwaj-Brysz, K; Lubelska, A; G?uch-Lutwin, M; Mordyl, B; Siwek, A; Nasim, MJ; Partyka, A; Sudo?, S; Latacz, G; Weso?owska, A; Kie?-Kononowicz, K; Handzlik, J Synthesis and computer-aided SAR studies for derivatives of phenoxyalkyl-1,3,5-triazine as the new potent ligands for serotonin receptors 5-HT Eur J Med Chem 178:740-751 (2019) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50516521
Synonyms:
CHEMBL4557247
Type:
Small organic molecule
Emp. Form.:
C15H20N6S
Mol. Mass.:
316.425
SMILES:
CN1CCN(CC1)c1nc(N)nc(CSc2ccccc2)n1
Structure:
Search PDB for entries with ligand similarity: