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Target
TYR_PHOSPHATASE_2 domain-containing protein
Ligand
BDBM50525978
Substrate
n/a
Meas. Tech.
ChEMBL_1898806 (CHEMBL4400921)
IC50
160±n/a nM
Citation
 Hou, XM; Wang, CY; Gerwick, WH; Shao, CL Marine natural products as potential anti-tubercular agents. Eur J Med Chem 165:273-292 (2019) [PubMed]  Article 
Target
Name:
TYR_PHOSPHATASE_2 domain-containing protein
Synonyms:
(PROTEIN-TYROSINE-PHOSPHATASE) (PTPase) | MPtpB | PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPB | Phosphotyrosine protein phosphatase | Phosphotyrosine-protein phosphatase PTPB | Protein Tyrosine Phosphatase PTPB
Type:
Hydrolase
Mol. Mass.:
30152.45
Organism:
Mycobacterium tuberculosis
Description:
n/a
Residue:
276
Sequence:
MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
  
Inhibitor
Name:
BDBM50525978
Synonyms:
CHEMBL3235985
Type:
Small organic molecule
Emp. Form.:
C21H18O8
Mol. Mass.:
398.3628
SMILES:
CC(=O)c1cc(C)c(O)c(Cc2c(O)cc(oc2=O)-c2ccc(O)c(O)c2)c1O
Structure:
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