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Target
Serine protease 1
Ligand
BDBM50084173
Substrate
n/a
Meas. Tech.
ChEMBL_212319 (CHEMBL815005)
Ki
260±n/a nM
Citation
 Guilford, WJ; Shaw, KJ; Dallas, JL; Koovakkat, S; Lee, W; Liang, A; Light, DR; McCarrick, MA; Whitlow, M; Ye, B; Morrissey, MM Synthesis, characterization, and structure-activity relationships of amidine-substituted (bis)benzylidene-cycloketone olefin isomers as potent and selective factor Xa inhibitors. J Med Chem 42:5415-25 (2000) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50084173
Synonyms:
2-[1-[4-amino(imino)methylphenyl]-(E)-methylidene]-6-[1-[4-amino(imino)methylphenyl]-(Z)-methylidene]-1-cyclohexanone | CHEMBL151049
Type:
Small organic molecule
Emp. Form.:
C22H22N4O
Mol. Mass.:
358.4363
SMILES:
NC(=N)c1ccc(\C=C2\CCC\C(=C/c3ccc(cc3)C(N)=N)C2=O)cc1
Structure:
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