Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM50085496
Substrate
n/a
Meas. Tech.
ChEMBL_155887 (CHEMBL769604)
IC50
9500±n/a nM
Citation
 Lucas, R; Ubeda, A; Payá, M; Alves, M; del Olmo, E; López, JL; San Feliciano, A Synthesis and enzyme inhibitory activities of a series of lipidic diamine and aminoalcohol derivatives on cytosolic and secretory phospholipases A2. Bioorg Med Chem Lett 10:285-8 (2000) [PubMed]  Article 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM50085496
Synonyms:
CHEMBL89162 | N*1*,N*1*-Diethyl-hexadecane-1,2-diamine | N1,N1-diethylhexadecane-1,2-diamine
Type:
Small organic molecule
Emp. Form.:
C20H44N2
Mol. Mass.:
312.5768
SMILES:
CCCCCCCCCCCCCCC(N)CN(CC)CC
Structure:
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