Reaction Details Report a problem with these data
Target
Adenosine kinase
Ligand
BDBM50094702
Substrate
n/a
Meas. Tech.
ChEMBL_217931 (CHEMBL822078)
Kd
3000000±n/a nM
Citation
 Hajduk, PJ; Gomtsyan, A; Didomenico, S; Cowart, M; Bayburt, EK; Solomon, L; Severin, J; Smith, R; Walter, K; Holzman, TF; Stewart, A; McGaraughty, S; Jarvis, MF; Kowaluk, EA; Fesik, SW Design of adenosine kinase inhibitors from the NMR-based screening of fragments. J Med Chem 43:4781-6 (2000) [PubMed]  Article 
Target
Name:
Adenosine kinase
Synonyms:
ADK | ADK_HUMAN
Type:
PROTEIN
Mol. Mass.:
40545.97
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1467841
Residue:
362
Sequence:
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH
  
Inhibitor
Name:
BDBM50094702
Synonyms:
1H-indole | CHEMBL15844 | Indol | Indole, 7 | indole
Type:
Small organic molecule
Emp. Form.:
C8H7N
Mol. Mass.:
117.1479
SMILES:
c1cc2ccccc2[nH]1
Structure:
Search PDB for entries with ligand similarity: