Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50096884
Substrate
n/a
Meas. Tech.
ChEBML_40026
Ki
3130±n/a nM
Citation
 Bezuglov, V; Bobrov, M; Gretskaya, N; Gonchar, A; Zinchenko, G; Melck, D; Bisogno, T; Di Marzo, V; Kuklev, D; Rossi, JC; Vidal, JP; Durand, T Synthesis and biological evaluation of novel amides of polyunsaturated fatty acids with dopamine. Bioorg Med Chem Lett 11:447-9 (2001) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50096884
Synonyms:
(9Z,12Z,15Z)-Octadeca-9,12,15-trienoic acid [2-(3,4-dihydroxy-phenyl)-ethyl]-amide | CHEMBL138040 | Linoleoyl dopamine
Type:
Small organic molecule
Emp. Form.:
C26H39NO3
Mol. Mass.:
413.5928
SMILES:
CC\C=C/C\C=C/C\C=C/CCCCCCCC(=O)NCCc1ccc(O)c(O)c1
Structure:
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