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Target
Potassium voltage-gated channel subfamily A member 3
Ligand
BDBM50083523
Substrate
n/a
Meas. Tech.
ChEMBL_214960 (CHEMBL821189)
IC50
230±n/a nM
Citation
 Butenschön, I; Möller, K; Hänsel, W Angular methoxy-substituted furo- and pyranoquinolinones as blockers of the voltage-gated potassium channel Kv1.3. J Med Chem 44:1249-56 (2001) [PubMed]  Article 
Target
Name:
Potassium voltage-gated channel subfamily A member 3
Synonyms:
KCNA3_MOUSE | Kcna3 | MK3 | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel subunit Kv1.3
Type:
PROTEIN
Mol. Mass.:
58553.58
Organism:
Mus musculus
Description:
ChEMBL_1513943
Residue:
528
Sequence:
MTVVPGDHLLEPEAAGGGGGDPPQGGCGSGGGGGGCDRYEPLPPALPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGAPSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
  
Inhibitor
Name:
BDBM50083523
Synonyms:
(1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine | CHEMBL281622 | CP-339818 | [1-Benzyl-1H-quinolin-(4E)-ylidene]-pentyl-amine
Type:
Small organic molecule
Emp. Form.:
C21H24N2
Mol. Mass.:
304.4287
SMILES:
CCCCC\N=c1/ccn(Cc2ccccc2)c2ccccc12
Structure:
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