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Target
Sulfotransferase 1E1
Ligand
BDBM50102703
Substrate
n/a
Meas. Tech.
ChEMBL_67847 (CHEMBL681339)
IC50
>200000±n/a nM
Citation
 Verdugo, DE; Cancilla, MT; Ge, X; Gray, NS; Chang, YT; Schultz, PG; Negishi, M; Leary, JA; Bertozzi, CR Discovery of estrogen sulfotransferase inhibitors from a purine library screen. J Med Chem 44:2683-6 (2001) [PubMed]  Article 
Target
Name:
Sulfotransferase 1E1
Synonyms:
Est | Estrogen sulfotransferase | ST1E1_MOUSE | Ste | Sult1e1
Type:
PROTEIN
Mol. Mass.:
35591.32
Organism:
Mus musculus
Description:
ChEMBL_67847
Residue:
295
Sequence:
METSMPEYYEVFGEFRGVLMDKRFTKYWEDVEMFLARPDDLVIATYPKSGTTWISEVVYMIYKEGDVEKCKEDAIFNRIPYLECRNEDLINGIKQLKEKESPRIVKTHLPPKLLPASFWEKNCKMIYLCRNAKDVAVSYYYFLLMITSYPNPKSFSEFVEKFMQGQVPYGSWYDHVKAWWEKSKNSRVLFMFYEDMKEDIRREVVKLIEFLERKPSAELVDRIIQHTSFQEMKNNPSTNYTMMPEEMMNQKVSPFMRKGIIGDWKNHFPEALRERFDEHYKQQMKDCTVKFRMEL
  
Inhibitor
Name:
BDBM50102703
Synonyms:
2-{6-[Bis-(2-hydroxy-ethyl)-amino]-9-methyl-9H-purin-2-ylamino}-acetamide(YTC27) | CHEMBL92115
Type:
Small organic molecule
Emp. Form.:
C12H19N7O3
Mol. Mass.:
309.3244
SMILES:
Cn1cnc2c(nc(NCC(N)=O)nc12)N(CCO)CCO
Structure:
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