Target
1-phosphatidylinositol phosphodiesterase
Ligand
BDBM50555554
Substrate
n/a
Meas. Tech.
ChEMBL_2052537 (CHEMBL4707538)
Kd
216000±n/a nM
Citation
 Eurtivong, CPilkington, LIvan Rensburg, MWhite, RMBrar, HKRees, SPaulin, EKXu, CSSharma, NLeung, IKHLeung, EBarker, DReynisson, J Discovery of novel phosphatidylcholine-specific phospholipase C drug-like inhibitors as potential anticancer agents. Eur J Med Chem 187:0 (2020) [PubMed]  Article 
Target
Name:
1-phosphatidylinositol phosphodiesterase
Synonyms:
1-phosphatidylinositol phosphodiesterase | 4.6.1.13 | PI-PLC | PLC_BACCE | Phosphatidylinositol diacylglycerol-lyase | Phosphatidylinositol-specific phospholipase C
Type:
PROTEIN
Mol. Mass.:
38110.25
Organism:
Bacillus cereus
Description:
ChEMBL_120142
Residue:
329
Sequence:
MSNKKLILKLFICSTIFITFVFALHDKRVVAASSVNELENWSKWMQPIPDSIPLARISIPGTHDSGTFKLQNPIKQVWGMTQEYDFRYQMDHGARIFDIRGRLTDDNTIVLHHGPLYLYVTLHEFINEAKQFLKDNPSETIIMSLKKEYEDMKGAEDSFSSTFEKKYFVDPIFLKTEGNIKLGDARGKIVLLKRYSGSNEPGGYNNFYWPDNETFTTTVNQNANVTVQDKYKVSYDEKVKSIKDTMDETMNNSEDLNHLYINFTSLSSGGTAWNSPYYYASYINPEIANYIKQKNPARVGWVIQDYINEKWSPLLYQEVIRANKSLIKE
  
Inhibitor
Name:
BDBM50555554
Synonyms:
CHEMBL4751563
Type:
Small organic molecule
Emp. Form.:
C8H11KOS2
Mol. Mass.:
226.401
SMILES:
[K;v0+].[#16-]-[#6](=S)-[#8]-[#6]-1-[#6]-[#6]-2-[#6]-[#6]-[#6]-1-[#6]-2
Structure:
Search PDB for entries with ligand similarity: