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Target
Phosphoglycerate mutase 1
Ligand
BDBM50557322
Substrate
n/a
Meas. Tech.
ChEMBL_2058835 (CHEMBL4713836)
IC50
2800±n/a nM
Citation
 Jiang, K; Gao, B; Yu, J; Jiang, L; Niu, A; Jia, Y; Meng, T; Zhou, L; Wang, J Design, synthesis, and biological evaluation of 1,3,6,7-tetrahydroxyxanthone derivatives as phosphoglycerate mutase 1 inhibitors. Bioorg Med Chem Lett 36:0 (2021) [PubMed]  Article 
Target
Name:
Phosphoglycerate mutase 1
Synonyms:
BPG-dependent PGAM 1 | PGAM-B | PGAM1 | PGAM1_HUMAN | PGAMA | Phosphoglycerate mutase 1 | Phosphoglycerate mutase isozyme B
Type:
PROTEIN
Mol. Mass.:
28806.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109479
Residue:
254
Sequence:
MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKAKK
  
Inhibitor
Name:
BDBM50557322
Synonyms:
CHEMBL4748271
Type:
Small organic molecule
Emp. Form.:
C20H20O6
Mol. Mass.:
356.3692
SMILES:
CCCCC=CCc1c(O)c(O)cc2oc3cc(O)cc(O)c3c(=O)c12
Structure:
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