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Target
Estrogen receptor beta
Ligand
BDBM50118995
Substrate
n/a
Meas. Tech.
ChEBML_67835
IC50
2100±n/a nM
Citation
 Smith, RA; Chen, J; Mader, MM; Muegge, I; Moehler, U; Katti, S; Marrero, D; Stirtan, WG; Weaver, DR; Xiao, H; Carley, W Solid-phase synthesis and investigation of benzofurans as selective estrogen receptor modulators. Bioorg Med Chem Lett 12:2875-8 (2002) [PubMed]  Article 
Target
Name:
Estrogen receptor beta
Synonyms:
ESR2_RAT | Erbeta | Esr2 | Estrogen receptor | Estrogen receptor beta | Nr3a2
Type:
PROTEIN
Mol. Mass.:
59173.80
Organism:
Rattus norvegicus
Description:
ChEMBL_803011
Residue:
530
Sequence:
MEIKNSPSSLSSPASYNCSQSILPLEHGPIYIPSSYVDNRHEYSAMTFYSPAVMNYSVPGSTSNLDGGPVRLSTSPNVLWPTSGHLSPLATHCQSSLLYAEPQKSPWCEARSLEHTLPVNRETLKRKLSGSSCASPVTSPNAKRDAHFCPVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRSSSEQVHCLSKAKRNGGHAPRVKELLLSTLSPEQLVLTLLEAEPPNVLVSRPSMPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLASANQEAESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVVPVYDLLLEMLNAHTLRGYKSSISGSECSSTEDSKNKESSQNLQSQ
  
Inhibitor
Name:
BDBM50118995
Synonyms:
(6-Hydroxy-3-phenyl-benzofuran-2-yl)-phenyl-methanone | CHEMBL98139
Type:
Small organic molecule
Emp. Form.:
C21H14O3
Mol. Mass.:
314.3341
SMILES:
Oc1ccc2c(c(oc2c1)C(=O)c1ccccc1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: