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Target
Serine protease 1
Ligand
BDBM50123037
Substrate
n/a
Meas. Tech.
ChEBML_212870
Ki
>1600±n/a nM
Citation
 Quan, ML; Ellis, CD; He, MY; Liauw, AY; Woerner, FJ; Alexander, RS; Knabb, RM; Lam, PY; Luettgen, JM; Wong, PC; Wright, MR; Wexler, RR Nonbenzamidine tetrazole derivatives as factor Xa inhibitors. Bioorg Med Chem Lett 13:369-73 (2003) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1
Type:
Enzyme
Mol. Mass.:
26557.80
Organism:
Homo sapiens (Human)
Description:
P07477
Residue:
247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
  
Inhibitor
Name:
BDBM50123037
Synonyms:
1-(3-Amino-benzo[d]isoxazol-5-yl)-1H-tetrazole-5-carboxylic acid (3-fluoro-2'-methanesulfonyl-biphenyl-4-yl)-amide | CHEMBL441283
Type:
Small organic molecule
Emp. Form.:
C22H16FN7O4S
Mol. Mass.:
493.47
SMILES:
CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)c2nnnn2-c2ccc3onc(N)c3c2)c(F)c1
Structure:
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