Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50129438
Substrate
n/a
Meas. Tech.
ChEBML_223734
Ki
3.5±n/a nM
Citation
 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists. Bioorg Med Chem Lett 13:2179-83 (2003) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3
Type:
Protein
Mol. Mass.:
49540.58
Organism:
Rattus norvegicus (Rat)
Description:
P19020
Residue:
446
Sequence:
MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLKRYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50129438
Synonyms:
6-Amino-9H-fluorene-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide | CHEMBL71502
Type:
Small organic molecule
Emp. Form.:
C28H30Cl2N4O
Mol. Mass.:
509.47
SMILES:
Nc1ccc2Cc3cccc(C(=O)NCCCCN4CCN(CC4)c4cccc(Cl)c4Cl)c3-c2c1
Structure:
Search PDB for entries with ligand similarity: