Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50569824
Substrate
n/a
Meas. Tech.
ChEMBL_2110427 (CHEMBL4819277)
Ki
754±n/a nM
Citation
 Sudo?, S; Kucwaj-Brysz, K; Kurczab, R; Wilczy?ska, N; Jastrz?bska-Wi?sek, M; Sata?a, G; Latacz, G; G?uch-Lutwin, M; Mordyl, B; ?es?awska, E; Nitek, W; Partyka, A; Buzun, K; Doroz-P?onka, A; Weso?owska, A; Bielawska, A; Handzlik, J Chlorine substituents and linker topology as factors of 5-HT Eur J Med Chem 203:0 (2020) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50569824
Synonyms:
CHEMBL4861431
Type:
Small organic molecule
Emp. Form.:
C16H20Cl2N6O
Mol. Mass.:
383.276
SMILES:
CC(Oc1ccc(Cl)c(Cl)c1)c1nc(N)nc(n1)N1CCN(C)CC1
Structure:
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