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Target
D(1A) dopamine receptor
Ligand
BDBM50135412
Substrate
n/a
Meas. Tech.
ChEBML_60516
IC50
>10000±n/a nM
Citation
 Baldwin, RM; Fu, X; Kula, NS; Baldessarini, RJ; Amici, L; Innis, RB; Tamagnan, GD Synthesis and affinity of a possible byproduct of electrophilic radiolabeling of [123I]IBZM. Bioorg Med Chem Lett 13:4015-7 (2003) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50135412
Synonyms:
CHEMBL423331 | N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-3-iodo-2-methoxy-benzamide
Type:
Small organic molecule
Emp. Form.:
C15H21IN2O3
Mol. Mass.:
404.2433
SMILES:
CCN1CCC[C@H]1CNC(=O)c1c(O)ccc(I)c1OC
Structure:
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