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Target
D(2) dopamine receptor
Ligand
BDBM50135711
Substrate
n/a
Meas. Tech.
ChEBML_60203
Ki
534±n/a nM
Citation
 Thurkauf, A; Chen, X; Zhang, S; Gao, Y; Kieltyka, A; Wasley, JW; Brodbeck, R; Greenlee, W; Ganguly, A; Zhao, H 1H-Pyrazolo-[3,4-c]cyclophepta[1,2-c]thiophenes: a unique structural class of dopamine D4 selective ligands. Bioorg Med Chem Lett 13:2921-4 (2003) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50135711
Synonyms:
7,9-Dichloro-1,4,5,6-tetrahydro-8-thia-1,2-diaza-cyclopenta[e]azulene | CHEMBL317770
Type:
Small organic molecule
Emp. Form.:
C10H8Cl2N2S
Mol. Mass.:
259.155
SMILES:
Clc1sc(Cl)c-2c1CCCc1c[nH]nc-21
Structure:
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