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Target
Genome polyprotein
Ligand
BDBM50137748
Substrate
n/a
Meas. Tech.
ChEMBL_161071 (CHEMBL771844)
Ki
190±n/a nM
Citation
 Lamar, J; Victor, F; Snyder, N; Johnson, RB; Wang, QM; Glass, JI; Chen, SH Novel P4 truncated tripeptidyl alpha-ketoamides as HCV protease inhibitors. Bioorg Med Chem Lett 14:263-6 (2003) [PubMed]  Article 
Target
Name:
Genome polyprotein
Synonyms:
Human rhinovirus A protease | Human rhinovirus B 3A protease
Type:
PROTEIN
Mol. Mass.:
44361.04
Organism:
Human rhinovirus B
Description:
ChEMBL_158953
Residue:
401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMSAIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIANIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVITTGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDRNEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYNYPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQTIHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
  
Inhibitor
Name:
BDBM50137748
Synonyms:
(1S,3aR,6aS)-2-((S)-3,3-Dimethyl-2-{(3S,4S)-3-methyl-2-[(pyrazine-2-carbonyl)-amino]-butyrylamino}-butyryl)-octahydro-cyclopenta[c]pyrrole-1-carboxylic acid [1-(1-phenyl-ethylaminooxalyl)-butyl]-amide | CHEMBL89835
Type:
Small organic molecule
Emp. Form.:
C38H53N7O6
Mol. Mass.:
703.8707
SMILES:
CCCC(NC(=O)[C@@H]1[C@H]2CCC[C@H]2CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)c1cnccn1)C(C)C)C(C)(C)C)C(=O)C(=O)N[C@@H](C)c1ccccc1
Structure:
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