Compile Data Set for Download or QSAR
maximum 50k data
Found 100 with Last Name = 'johnson' and Initial = 'rb'
TargetCathepsin B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137733((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  1.60nMAssay Description:Inhibitory activity of the compound against cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137736((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  3.70nMAssay Description:Inhibitory activity of the compound against cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137720((1S,3aR,6aS)-2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(p...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity of the compound against cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137730((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity of the compound against cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150593(3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (S)-...)
Affinity DataKi:  6.10nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137720((1S,3aR,6aS)-2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(p...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity of the compound against cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150591((S)-2-{(S)-3-Methyl-2-[(S)-3-methyl-2-(5-1H-tetraz...)
Affinity DataKi:  22nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137747((1S,3aR,6aS)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2...)
Affinity DataKi:  23nMAssay Description:Binding affinity towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137732((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  29nMAssay Description:Inhibitory activity of the compound against cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150599(2-{(S)-2-[(S)-2-Cyclohexyl-2-(2-2H-tetrazol-5-yl-a...)
Affinity DataKi:  30nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137730((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity of the compound against cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150595((S)-2-{(S)-3-Methyl-2-[(S)-3-methyl-2-(5-1H-tetraz...)
Affinity DataKi:  31nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137732((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  52nMAssay Description:Inhibitory activity of the compound against cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137736((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  52nMAssay Description:Inhibitory activity of the compound against cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137732((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  62nMAssay Description:Inhibitory activity of the compound against ChymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150606(3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (S)-...)
Affinity DataKi:  65nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150602(3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (S)-...)
Affinity DataKi:  74nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150604(2-{(S)-3-Methyl-2-[(S)-3-methyl-2-(5-1H-tetrazol-5...)
Affinity DataKi:  82nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137739((1S,3aR,6aS)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2...)
Affinity DataKi:  84nMAssay Description:Binding affinity towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137733((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  84nMAssay Description:Binding affinity of the compound towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150605(CHEMBL360805 | Naphthalene-2-carboxylic acid (S)-1...)
Affinity DataKi:  110nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150598((S)-2-{(S)-3-Methyl-2-[(S)-3-methyl-2-(5-1H-tetraz...)
Affinity DataKi:  112nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137738((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  120nMAssay Description:Binding affinity of the compound towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137720((1S,3aR,6aS)-2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(p...)
Affinity DataKi:  120nMAssay Description:Binding affinity of the compound towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150601(2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(pyrazine-2-car...)
Affinity DataKi:  123nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137720((1S,3aR,6aS)-2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(p...)
Affinity DataKi:  123nMAssay Description:Cytotoxic activity in rat liver Huh-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137733((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  154nMAssay Description:Inhibitory activity of the compound against cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150594((S)-2-{(S)-3-Methyl-2-[(S)-3-methyl-2-(5-1H-tetraz...)
Affinity DataKi:  170nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137748((1S,3aR,6aS)-2-((S)-3,3-Dimethyl-2-{(3S,4S)-3-meth...)
Affinity DataKi:  190nMAssay Description:Binding affinity towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137732((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  190nMAssay Description:Binding affinity of the compound towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150607(3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (S)-...)
Affinity DataKi:  193nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137730((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  200nMAssay Description:Binding affinity of the compound towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137736((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  210nMAssay Description:Binding affinity of the compound towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137729((1S,5S,6R)-2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(pyr...)
Affinity DataKi:  220nMAssay Description:Inhibitory activity of the compound against HCV protease using replicon assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137732((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  229nMAssay Description:Inhibitory activity of the compound against cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150590((S)-2-{(S)-3-Methyl-2-[(S)-3-methyl-2-(5-1H-tetraz...)
Affinity DataKi:  248nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137744(CHEMBL328740 | {(S)-1-[(1S,3aR,6aS)-4,4-Difluoro-1...)
Affinity DataKi:  270nMAssay Description:Binding affinity towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150597(3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (S)-...)
Affinity DataKi:  271nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137730((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  303nMAssay Description:Inhibitory activity of the compound against ChymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137735((1S,5S,6R)-2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(pyr...)
Affinity DataKi:  380nMAssay Description:Binding affinity of the compound towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137734((1S,5S,6R)-2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(pyr...)
Affinity DataKi:  400nMAssay Description:Binding affinity of the compound towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150600(CHEMBL360747 | Naphthalene-2-carboxylic acid (S)-5...)
Affinity DataKi:  400nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150596(3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (S)-...)
Affinity DataKi:  404nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137741(CHEMBL84855 | {(S)-2-Methyl-1-[(1S,3aR,6aS)-1-(1-p...)
Affinity DataKi:  420nMAssay Description:Binding affinity towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137737((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  480nMAssay Description:Inhibitory activity of the compound against HCV protease using replicon assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137733((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  492nMAssay Description:Inhibitory activity of the compound against cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137720((1S,3aR,6aS)-2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(p...)
Affinity DataKi:  583nMAssay Description:Inhibitory activity of the compound against ChymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137720((1S,3aR,6aS)-2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(p...)
Affinity DataKi:  683nMAssay Description:Inhibitory activity of the compound against cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50150603((S)-2-{(S)-3,3-Dimethyl-2-[(S)-3-methyl-2-(2-2H-te...)
Affinity DataKi:  808nMAssay Description:Inhibitory potency against HCV NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137740(CHEMBL89106 | {(S)-2,2-Dimethyl-1-[(1S,3aR,6aS)-1-...)
Affinity DataKi:  820nMAssay Description:Binding affinity towards Protease using PNA assay in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 100 total ) | Next | Last >>
Jump to: