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Target
Metallo-beta-lactamase type 2
Ligand
BDBM26116
Substrate
n/a
Meas. Tech.
ChEMBL_104645 (CHEMBL712891)
IC50
21800±n/a nM
Citation
 Buynak, JD; Chen, H; Vogeti, L; Gadhachanda, VR; Buchanan, CA; Palzkill, T; Shaw, RW; Spencer, J; Walsh, TR Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases. Bioorg Med Chem Lett 14:1299-304 (2004) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase type 2
Synonyms:
BLAB_BACCE | Beta-lactamase 2 | Metallo-beta-lactamase domain-containing protein 2 | Metallo-beta-lactamase superfamily protein
Type:
PROTEIN
Mol. Mass.:
28044.00
Organism:
Bacillus cereus
Description:
ChEMBL_104097
Residue:
256
Sequence:
MKNTLLKLGVCVSLLGITPFVSTISSVQAERTVEHKVIKNETGTISISQLNKNVWVHTELGYFSGEAVPSNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEKKFKKRVTDVIITHAHADRIGGMKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQSVTNLKFGNMKVETFYPGKGHTEDNIVVWLPQYQILAGGCLVKSASSKDLGNVADAYVNEWSTSIENVLKRYGNINLVVPGHGEVGDRGLLLHTLDLLK
  
Inhibitor
Name:
BDBM26116
Synonyms:
CHEMBL284104 | Dipicolinate | pyridine carboxylate, 6d | pyridine-2,6-dicarboxylic acid
Type:
Small organic molecule
Emp. Form.:
C7H5NO4
Mol. Mass.:
167.1189
SMILES:
OC(=O)c1cccc(n1)C(O)=O
Structure:
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