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Target
Bcl-2-related protein A1
Ligand
BDBM50576622
Substrate
n/a
Meas. Tech.
ChEMBL_2127592 (CHEMBL4836937)
Kd
>10000±n/a nM
Citation
 Zhu, PJ; Yu, ZZ; Lv, YF; Zhao, JL; Tong, YY; You, QD; Jiang, ZY Discovery of 3,5-Dimethyl-4-Sulfonyl-1 J Med Chem 64:11330-11353 (2021) [PubMed]  Article 
Target
Name:
Bcl-2-related protein A1
Synonyms:
B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:
Apoptosis regulator protein
Mol. Mass.:
20130.01
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
  
Inhibitor
Name:
BDBM50576622
Synonyms:
CHEMBL4850731
Type:
Small organic molecule
Emp. Form.:
C26H28ClNO6S
Mol. Mass.:
518.022
SMILES:
CC(=O)c1ccc(cc1)S(=O)(=O)c1c(C)c(C(O)=O)n(CCCOc2cc(C)c(Cl)c(C)c2)c1C
Structure:
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