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Target
D(3) dopamine receptor
Ligand
BDBM50578339
Substrate
n/a
Meas. Tech.
ChEMBL_2132592 (CHEMBL4842107)
EC50
13±n/a nM
Citation
 Yan, W; Fan, L; Yu, J; Liu, R; Wang, H; Tan, L; Wang, S; Cheng, J 2-Phenylcyclopropylmethylamine Derivatives as Dopamine D J Med Chem 64:17239-17258 (2021) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3 | DRD3_HUMAN | Dopamine D3 receptor
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Homo sapiens
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50578339
Synonyms:
CHEMBL4875081
Type:
Small organic molecule
Emp. Form.:
C23H25ClN2O3
Mol. Mass.:
412.909
SMILES:
COc1ccc(Cl)cc1[C@H]1C[C@@H]1CNCCCOc1ccc2ccc(=O)[nH]c2c1 |r|
Structure:
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