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Target
Relaxin-3 receptor 2
Ligand
BDBM50581020
Substrate
n/a
Meas. Tech.
ChEMBL_2149557 (CHEMBL5033955)
EC50
0.900000±n/a nM
Citation
 Guan, D; Rahman, MT; Gay, EA; Vasukuttan, V; Mathews, KM; Decker, AM; Williams, AH; Zhan, CG; Jin, C Indole-Containing Amidinohydrazones as Nonpeptide, Dual RXFP3/4 Agonists: Synthesis, Structure-Activity Relationship, and Molecular Modeling Studies. J Med Chem 64:17866-17886 (2021) [PubMed]  Article 
Target
Name:
Relaxin-3 receptor 2
Synonyms:
G-protein coupled receptor 100 | G-protein coupled receptor GPCR142 | GPCR142 | GPR100 | Insulin-like peptide INSL5 receptor | RL3R2_HUMAN | RLN3 receptor 2 | RLN3R2 | RXFP4 | Relaxin family peptide receptor 4
Type:
PROTEIN
Mol. Mass.:
41161.14
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1456194
Residue:
374
Sequence:
MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTAVFGVEGEVCGVRLCLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQRRQRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRLRLWPQGGGWVQQVALKQVGRRWVASNPRESRPSTLLTNLDRGTPG
  
Inhibitor
Name:
BDBM50581020
Synonyms:
CHEMBL5094669
Type:
Small organic molecule
Emp. Form.:
C20H21N7
Mol. Mass.:
359.4276
SMILES:
CCc1cc(cc2c(\C=N\NC(=N)NCCc3cccnc3)c[nH]c12)C#N
Structure:
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