Found 384 with Last Name = 'guan' and Initial = 'd' 
Affinity DataKi: 11nMAssay Description:Displacement of [125I]R3/I5 from human RXFP3 expressed in CHO-K1 cells membrane assessed as inhibition constant incubated for 1 hr by microplate scin...More data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Displacement of [125I]R3/I5 from human RXFP3 expressed in human CHO-K1 cells incubated for 1 hr by microplate scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 268nMAssay Description:Displacement of [125I]R3/I5 from human RXFP3 expressed in human CHO-K1 cells incubated for 1 hr by microplate scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 274nMAssay Description:Displacement of [125I]R3/I5 from human RXFP3 expressed in human CHO-K1 cells incubated for 1 hr by microplate scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.51E+3nMAssay Description:Displacement of [125I]R3/I5 from human RXFP3 expressed in human CHO-K1 cells incubated for 1 hr by microplate scintillation counting analysisMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of sigma-2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 0.700nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of TRKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 1.10nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.42nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
Affinity DataIC50: 1.49nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 2.60nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 2.70nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:The degree of inhibition of the enzymatic activity of recombinant human ACC1, ACC2 proteins under in-vitro conditions by the preferred compounds of t...More data for this Ligand-Target Pair
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of TRKB (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.31nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
Affinity DataIC50: 3.65nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:The degree of inhibition of the enzymatic activity of recombinant human ACC1, ACC2 proteins under in-vitro conditions by the preferred compounds of t...More data for this Ligand-Target Pair
Affinity DataIC50: 4.58nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 4.90nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 5nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
TargetNT-3 growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of wild type TRKC (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of wild type TRKB (unknown origin)More data for this Ligand-Target Pair
TargetNT-3 growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of TRKC (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 5nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 5nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:The degree of inhibition of the enzymatic activity of recombinant human ACC1, ACC2 proteins under in-vitro conditions by the preferred compounds of t...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 6.20nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
Affinity DataIC50: 6.35nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:The degree of inhibition of the enzymatic activity of recombinant human ACC1, ACC2 proteins under in-vitro conditions by the preferred compounds of t...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 6.80nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
Affinity DataIC50: 6.92nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
