Reaction Details Report a problem with these data
Target
Tubulin beta chain [1-43]
Ligand
BDBM50156484
Substrate
n/a
Meas. Tech.
ChEMBL_311631 (CHEMBL833941)
IC50
40000±n/a nM
Citation
 Kim, S; Park, JH; Koo, SY; Kim, JI; Kim, MH; Kim, JE; Jo, K; Choi, HG; Lee, SB; Jung, SH Novel diarylsulfonylurea derivatives as potent antimitotic agents. Bioorg Med Chem Lett 14:6075-8 (2004) [PubMed]  Article 
Target
Name:
Tubulin beta chain [1-43]
Synonyms:
Beta tubulin | TBB_LEIME
Type:
PROTEIN
Mol. Mass.:
4652.47
Organism:
Leishmania donovani
Description:
ChEMBL_311916
Residue:
43
Sequence:
MREIVSCQAGQCGNQIGSKFWEVIADEHGVDPTGSYQGDSDLQ
  
Inhibitor
Name:
BDBM50156484
Synonyms:
(S)-1-[1-(5-Nitro-furan-2-carbonyl)-2,3-dihydro-1H-indole-5-sulfonyl]-4-phenyl-imidazolidin-2-one | CHEMBL188420
Type:
Small organic molecule
Emp. Form.:
C22H18N4O7S
Mol. Mass.:
482.466
SMILES:
[O-][N+](=O)c1ccc(o1)C(=O)N1CCc2cc(ccc12)S(=O)(=O)N1C[C@@H](NC1=O)c1ccccc1
Structure:
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