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Target
Somatostatin receptor type 1
Ligand
BDBM50159423
Substrate
n/a
Meas. Tech.
ChEMBL_306609 (CHEMBL829069)
IC50
22±n/a nM
Citation
 Erchegyi, J; Hoeger, CA; Low, W; Hoyer, D; Waser, B; Eltschinger, V; Schaer, JC; Cescato, R; Reubi, JC; Rivier, JE Somatostatin receptor 1 selective analogues: 2. N(alpha)-Methylated scan. J Med Chem 48:507-14 (2005) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1)
Type:
Enzyme
Mol. Mass.:
42692.81
Organism:
Homo sapiens (Human)
Description:
P30872
Residue:
391
Sequence:
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL
  
Inhibitor
Name:
BDBM50159423
Synonyms:
CHEMBL440066 | Des-AA1,2,5-[D-Nal8,(NalphaMe)IAmp9,Tyr11]Cbm-SRIF
Type:
Small organic molecule
Emp. Form.:
C77H100N14O15S2
Mol. Mass.:
1525.833
SMILES:
CC(C)NCc1ccc(C[C@@H]2N(C)C(=O)[C@H](Cc3ccc4ccccc4c3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@H](NC2=O)[C@@H](C)O)[C@@H](C)O)C(N)=O)cc1
Structure:
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