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Target
Cyclin-dependent kinase 1
Ligand
BDBM50434356
Substrate
n/a
Meas. Tech.
ChEMBL_2213893 (CHEMBL5127025)
IC50
>10000±n/a nM
Citation
 Haghighijoo, Z; Zamani, L; Moosavi, F; Emami, S Therapeutic potential of quinazoline derivatives for Alzheimer's disease: A comprehensive review. Eur J Med Chem 227:0 (2022) [PubMed] 
Target
Name:
Cyclin-dependent kinase 1
Synonyms:
CDC2 | CDC28A | CDK1 | CDK1_HUMAN | CDKN1 | Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | P34CDC2 | p34 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
34101.08
Organism:
Homo sapiens (Human)
Description:
P06493
Residue:
297
Sequence:
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
  
Inhibitor
Name:
BDBM50434356
Synonyms:
CHEMBL2386744 | US9446044, 44
Type:
Small organic molecule
Emp. Form.:
C17H11BrFN5OS
Mol. Mass.:
432.27
SMILES:
COC(=N)c1nc2ccc3ncnc(Nc4ccc(Br)cc4F)c3c2s1
Structure:
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