Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50603612
Substrate
n/a
Meas. Tech.
ChEMBL_2244553 (CHEMBL5158763)
Ki
6820±n/a nM
Citation
 Abel, B; Murakami, M; Tosh, DK; Yu, J; Lusvarghi, S; Campbell, RG; Gao, ZG; Jacobson, KA; Ambudkar, SV Interaction of A Eur J Med Chem 231:0 (2022) [PubMed] 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50603612
Synonyms:
CHEMBL5171777
Type:
Small organic molecule
Emp. Form.:
C20H16ClN5O2S
Mol. Mass.:
425.891
SMILES:
COc1cc(CCNC2=NC(=NC3=NC=NC23)C#Cc2ccc(Cl)s2)ccc1O |c:10,14,t:8,12|
Structure:
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