Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50603613
Substrate
n/a
Meas. Tech.
ChEMBL_2244553 (CHEMBL5158763)
Ki
483±n/a nM
Citation
 Abel, B; Murakami, M; Tosh, DK; Yu, J; Lusvarghi, S; Campbell, RG; Gao, ZG; Jacobson, KA; Ambudkar, SV Interaction of A Eur J Med Chem 231:0 (2022) [PubMed] 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50603613
Synonyms:
CHEMBL5169644
Type:
Small organic molecule
Emp. Form.:
C31H30N4O4
Mol. Mass.:
522.5943
SMILES:
[H][C@]12C[C@@]1([C@@H](O)[C@@H](O)[C@@H]2n1ccc2c(NCCc3ccccc3)nc(nc12)C#Cc1ccccc1)C(=O)OCC |r|
Structure:
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