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Target
S-ribosylhomocysteine lyase
Ligand
BDBM50148771
Substrate
n/a
Meas. Tech.
ChEMBL_353579 (CHEMBL861694)
Ki
720000±n/a nM
Citation
 Shen, G; Rajan, R; Zhu, J; Bell, CE; Pei, D Design and synthesis of substrate and intermediate analogue inhibitors of S-ribosylhomocysteinase. J Med Chem 49:3003-11 (2006) [PubMed]  Article 
Target
Name:
S-ribosylhomocysteine lyase
Synonyms:
LUXS_ECOLI | luxS | ygaG
Type:
PROTEIN
Mol. Mass.:
19410.45
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_353579
Residue:
171
Sequence:
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
  
Inhibitor
Name:
BDBM50148771
Synonyms:
(2R,3R)-N,2,3,4-TETRAHYDROXYBUTANAMIDE | (2R,4R)-2,3,4,N-Tetrahydroxy-butyramide | CHEMBL117442 | D-erythronohydroxamic acid
Type:
Small organic molecule
Emp. Form.:
C4H9NO5
Mol. Mass.:
151.118
SMILES:
OC[C@@H](O)[C@@H](O)C(=O)NO
Structure:
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